Molecular Formula | C4H4ClN3O3S2 |
Molar Mass | 241.67586 |
Density | 1.788±0.06 g/cm3(Predicted) |
Melting Point | 230 °C |
Solubility | Methanol; DMSO; DMF; |
Appearance | Solid |
Color | Off-white |
pKa | 8.58±0.50(Predicted) |
Use | an intermediate of acetazolamide. |
production method | condensation and rearrangement of hydrazine sulfate and ammonium thiocyanate to produce dithiourea, then catalytic cyclization of 2-amino -5-mercapto-1, 3, 4-thiadiazole, and then acetic anhydride and acetic acid to the amino group acetylation and chlorine and water to the thiol oxidation, the product was prepared by chlorination. |